Colibra™ - precision fabrication of complex libraries


There is little point in designing complex state-of-the-art libraries if advanced features, designed to maximise functionality and minimise errors and liabilities, cannot be reliably incorporated into the final library build.


The incorporation of stop codons and frame-shifts are a common feature of using degenerate oligonucleotides whilst poor control of codon incorporation is a feature of using TRIM technology.

Isogenica’s Colibra™ technology ensures libraries are built with precise codon ratio control at each variant position, surpassing other approaches and ensuring the accurate realisation of the library design.

As a result libraries built with Colibra™ offer unprecedented opportunities to maximise active functional diversity.

Translating design into reality
Reducing unwanted liabilities in lead antibodies


Antibody Engineering & Therapeutics

San Diego, USA | 11th - 15th December 2016
Isogenica is pleased to be attending and presenting at this event and looks forward to meeting you

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London, UK | 1st December 2016
Isogenica is pleased to be attending this event and looks forward to meeting you

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Isogenica announces new discovery program with Molecular Templates

Cambridge, UK | 16th March 2016.


Isogenica and Molecular Templates of Georgetown, TX, have initiated a research program whereby Isogenica will use its...

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New Chief Scientific Officer

Cambridge, UK | 1st January 2016.


Isogenica is delighted to announce the strengthening of its management team with the appointment of Dr Guy Hermans as Chief Scientific Officer.

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