Colibra™ - precision fabrication of complex libraries


There is little point in designing complex state-of-the-art libraries if advanced features, designed to maximise functionality and minimise errors and liabilities, cannot be reliably incorporated into the final library build.


The incorporation of stop codons and frame-shifts are a common feature of using degenerate oligonucleotides whilst poor control of codon incorporation is a feature of using TRIM technology.

Isogenica’s Colibra™ technology ensures libraries are built with precise codon ratio control at each variant position, surpassing other approaches and ensuring the accurate realisation of the library design.

As a result libraries built with Colibra™ offer unprecedented opportunities to maximise active functional diversity.

Translating design into reality
Reducing unwanted liabilities in lead antibodies


PEGS Boston 2017

Boston, USA | 1st - 5th May 2016
Isogenica is pleased to be attending and presenting at this event and looks forward to meeting you

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10th Annual Proteins & Antibodies Congress 2017

London, UK | 24th-25th April 2017
Isogenica is pleased to be attending and speaking at this event and looks forward to meeting you

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Isogenica’s llamdA™ VHH library now available in phage display format

Cambridge, UK | 4th November 2016.


Isogenica’s llamdA™ VHH library is now also available in phage display format...

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Isogenica signs two further agreements utilizing CIS display

Cambridge, UK | 1st November 2016.


Isogenica has recently signed with two separate biotech companies to use its proprietary CIS display platform...

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