Proprietary Technology

Colibra™ - precision fabrication of complex libraries

 

There is little point in designing complex state-of-the-art libraries if advanced features, designed to maximise functionality and minimise errors and liabilities, cannot be reliably incorporated into the final library build.

 

The incorporation of stop codons and frame-shifts are a common feature of using degenerate oligonucleotides whilst poor control of codon incorporation is a feature of using TRIM technology.


Isogenica’s Colibra™ technology ensures libraries are built with precise codon ratio control at each variant position, surpassing other approaches and ensuring the accurate realisation of the library design.


As a result libraries built with Colibra™ offer unprecedented opportunities to maximise active functional diversity.


Translating design into reality
Reducing unwanted liabilities in lead antibodies