Research-Focused Blog Posts
Our blog posts offer concise, expert commentary on the latest developments in VHH technology. From new research findings to industry updates and practical tips, each article is written to inform and support your scientific work.
Llamas: leading the pack in new cancer therapy, BioScience Today’s article on Isogenica’s VHH discovery
Llamas: leading the pack in new cancer therapy, BioScience Today’s article on Isogenica’s VHH discovery
Small and mighty – VHH ‘bolt-ons’ to expand therapeutic functionality
Small antibody building blocks: VHHs or “Nanobodies” are single domain antibodies about 1/10th the size of an IgG. Combined with their robust biophysical properties and high solubiltiy, the simplicity of these molecules…
The golden age of bi-specific antibodies is here
Bi-specific antibodies (BsAbs) – antibodies that can recognise two different epitopes on either the same or different antigens – have been around for a long time. However, in the past few years we’ve seen a renaissance in the design and application of these molecules.
On the Origin of VHHs: Student serendipity and coincidental camels
We explain how VHHs – small format single-domain antibody fragments – have a range of unique properties that make them ideal for enhancing the therapeutic potential of conventional IgG antibodies.
Isogenica turns 25: Our journey
We’ve come a long way over the past quarter century, from our early years as a therapeutic peptide discovery company to specialising in VHH antibodies. Here’s the story…
Advantages of using VHH antibodies for CAR engineering
We explain the advantages of VHHs for CAR ectodomain targeting relative to traditional scFvs including size, solubility, and VHHs unique “magic finger” CDR3 domain.