CIS Display

CIS display is an antibody selection tool and alternative to traditional phage display methods.

What is CIS display?

 

Unlike phage, yeast, or mammalian display, CIS display does not involve a biological system. This means that library sizes are less restricted and that larger libraries can be mined effectively.

Originally developed by a team at Isogenica including our current CEO Dr. Bill Eldridge, CIS display was first designed to interrogate high-diversity peptide libraries. Over time, this was extended very successfully to increasingly complex small format scaffolds such as Centyrins and VHHs.

 

 

Why do we use CIS display?

 

CIS display is the perfect partner for our synthetic libraries to enable much faster antibody discovery compared to immunisation. To learn more, get in touch today.

Publications