by Isogenica Webmaster | Sep 2023 | Bi-specific resources, Blogs, VHHs
The golden age of bi-specific antibodies is here Bi-specific antibodies (BsAbs) – antibodies that can recognise two different epitopes on either the same or different antigens – have been around for a long time. However, in the past few years we’ve seen a...
by Isogenica Webmaster | Sep 2023 | Blogs, VHH Resources, VHHs
On the Origin of VHHs: Student serendipity and coincidental camels At Isogenica, we’re experts in discovering and developing VHHs – small format single chain antibodies. Unlike conventional IgG antibodies from humans or mice, VHHs (also known as nanobodies) are...
by Isogenica Webmaster | May 2023 | Blogs, Welcome
Isogenica turns 25: Our journey We’ve come a long way over the past quarter century, from our early years as a therapeutic peptide discovery company to specialising in VHH antibodies. Like many long-standing businesses, we’ve been through many changes to get to where...
by Philippa Shelton | Sep 2022 | Blogs, CAR-T, VHH Resources
Advantages of using VHH antibodies for CAR engineering Since the first anti-CD19 CAR-T cell therapy was approved in 2017, there’s been an explosion of interest in using engineered immune cells to treat cancer. CAR constructs consist of an external antibody-based...