by Isogenica Webmaster | May 2024 | Blogs, Case studies, VHH Affinity Maturation and Engineering
2-for-1 VHH antibody engineering Humanising and improving antibody affinity all in one step Sometimes the smallest of molecules pose the greatest challenges. This was the case when a partner approached us with what turned out to be a VHH antibody engineering...
by Isogenica Webmaster | May 2024 | Bi-specific resources, Blogs, VHH Affinity Maturation and Engineering, VHHs
VHH Humanisation Unlike conventional IgG antibodies from humans or mice, VHHs (also known as nanobodies) are composed solely of the single variable domain of a heavy chain. Originally derived from llamas, VHH antibody humanisation is often required. Here we compare...
